basic proprietates

Product #	Afatinib
Number CAS	439081, 18 2,
Molecular Formula	C24H25ClFN5O3
Pondus formulae	485.9
definition	Afatinib; 439081, 18, 2; 850140, 72, 6; BIBW2992; Tovok.
aspectus	Album crystallinum pulveris
Tractantem et repono	Et comportabis apud te ad locus temperatus a humorem, et excessus calor.

 

Afatinib Description

Afatinib, venundatus sub notam nomen Gilotrif apud alios, is utendum est medicamento tractare parva non-cell carcinoma, quod pulmone (NSCLC) Matrix enzyme tyrosine It pertinet ad familiam Dei capta est per os medications.It.

Et facies casibus de portu qui NSCLC Afatinib maxime ad mutationes in in epidermal incrementum factor (EGFR) gene.

 

Vitro Afatinib

Et velut lapatinib neratinib, afatinib est enim precursor protein eum irrepetibili modo etiam nia homo epidermalibus incrementum factor II (Her2) et incrementum epidermalibus factor (EGFR) kinases. Afatinib, non solum active in-tyrosine enzyme EGFR mutationes targeted per primam sui generationem inhibitors (TKIs) ut vel erlotinib gefitinib, in minus communi, sed etiam mutationibus quae repugnant, ea medicamenta. Sed omnino non agit contra mutationem T2M requiritur insuper ipsius operationis ad tertiam osimertinib.Because Her790 mauris similis est perspectis pro pectus cancer et EGFR aliisque Her2 agitatae carcinomata.

 

Application Afatinib

Quia usu receptum est regulatory approbatione Afatinib in cellula parva curatio est non-pulmonis cancer, est tamen usus in aliis carcinomata sua emergentes indicio suscipere huiusmodi ut pectus cancer.

 

Monitum Afatinib parte effectus &

Ipsum communi (> X% frequency)

▪ Diarrhoea (> XC%)

▪ temeraria / DERMATITIS acneform

▪ Stomatitis

▪ Paronychie

Decrescebat appetitus ▪

▪ Naribus minuo

▪ itchiness

Arida cutis ▪

 

Communi (1-10% frequency)

▪ siccitatibus conveniunt, Gustate mutationes, arida oculus

▪ CYSTITIS, Cheilitis: Rebus Fever

▪ Fefo / stuffy nasus

Minimum ▪ moles kalium in sanguinem

▪ Conjunctivitis

▪ Auxit ALT

▪ Auxit AST

▪ manu pedem syndrome,

▪ Musculus nervorum distentiones

Renibus ▪ corruptionem pertinent et / vel defectum,

 

Rare (0.1-1% frequency)

▪ kERATITIS

Interstitial ▪ pulmonis morbo,

 

Reference

[I] "Gilotrif (afatinib) Tablet, film iactaret". DailyMed. Boehringer Ingelheim Pharmaceuticals, Inc. 1. XVIII Octobris Receptum MMXX November IV.

[II] Spreitzer C (MMVIII May XIII). "Neue Wirkstoffe - Tovok". Osterreichische Apothekerzeitung (germanice) (2/13) CDXCVIII

[III] Minkovsky N, A Berezov (December MMVIII). "BIBW, MMCMXCII, duplex curatio receptor kinase precursor ad solidum ex parte corporis." Medicamenta in Investigational humanarum opinionum vel peritissimus. IX (XII): 3-2008. PMID 2992.

[IV] "Afatinib". US Cibus et medicamentis Administration. July XII 4. [dead link] [V] «Giotrif Afatinib (ut afatinib dimaleate)" (PDF). TGA eBusiness Services. Boehringer Ingelheim Pty Ltd. November XXVIII 12. Receptum VII January MMXIV.

[VI] Vavalà T (MMXVII). 'Munus in afatinib curatio provectus pulmonis ex Plattenepithelkarzinom ". Materia Medica orci. IX, 6-2017. doi: 9 / CPAA.S147. PMC 157. PMID 10.2147.

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